well so far the MegaSquirt is working out good - just time consuming - idk how much you already know about the MS, but check out these sites if you havnt already:
http://www.diyautotune.com/,
http://www.megamanual.com/index.html
the biggest thing with the MS on the RB is that you cant use the CAS for timing - i am using a 36-1 trigger wheel mounted on the crank pulley and a VR sensor to control timing - this is the setup that is used on Fords - they sell the trigger wheels on the first link i posted - also i am using the Ford EDIS ignition module to control the GM waste spark setup i have. the reason for the EDIS is that MS has proven it to work- and idk if the Nissan igniter would work, it should im just not positive as to how. i have not installed either the trigger wheel or the EDIS yet but as soon as i do i will post more updates
as for my rear end - unfortunately it is the stock 7.5" garbage rear end - i am planning on swapping it for a GM 8.5" rear end with a locker since o guy i work with has the rear end laying around - with stock suspension in my S10 i had wheel hop but now i have it lowered 5" all around with Belltech suspension and i dont get wheel hop anymore -