All of the Honda/Toyota/Nissan/Mazda long life and super long life coolants are P-OAT coolants formulated by CCI

It's big to understand that color doesn't matter. While most Organic Acid Technology (OAT) coolants are usually orange, yellow, red or purple, Hybrid Organic Acid Technology (HOAT) coolants are orange and yellow. There's quite a bit of overlap. Then you have Inorganic Acid Technology (IAT) coolants that are usually green, however, some manufacturers sell them in blue. At the end of the day, always be sure to read the bottle to confirm the type of coolant you're using. When looking for the right coolant for your 2018 Nissan Rogue, you need to always check your owner's manual.

Prestone Regular or 50/50 is a silicate free OAT antifreeze. It uses phosphates to replace the silicates.

Ultimately it isn't the color but the composition that matters. It was confusing for a while, but since most of the industry went to OAT you can't go far wrong with any name brand off-the-shelf coolant. The US and Japan are on the same page in 2013.

"The dye color of antifreeze has nothing to do with antifreeze formula or performance. Chrysler’s G-05 contains orange dye to distinguish it from a yellow dye antifreeze previously used. Other users of G-05 have yellow or even blue dye. However, GM DexCool, a purely organic acid type, also has orange dye, and this has been a source of service industry confusion. Fiat’s OAT, although a different formula, also has orange dye and it has been used in early production of the Dodge Dart. The new Chrysler OAT, however, will have a purple dye."

It's far more important to use distilled water, which is less than a dollar per gallon and often overlooked in this discussion. Tap water contains minerals you don't want.

So what gives Prestone the confidence to state "all makes and models?" It contains phosphates, not silicates, so it is safe to use in a Japanese car's cooling system. It can also be used in any non-Japanese car as long as North American water is used! So to support its claim Prestone merely specifies that its coolant be used in North America! Simple.