I mean, sure..I guess 22" wheels would fill up the fenders.. :P
it would have to be a heinously large wheel/tire combo to noticably affect the actual fender gap pf the vehicle. most of the time a 17" wheels/tire comba looks like its got more fender gap, because its an optical illusion creaded by the larger wheel...
but seriously, if you LIKE the stock wheels, keep them, run a 215-55-15 or 205-55-15 or whatever size you want to run, and lower the car to your liking, its both cheaper, and better than trying to fill the gap with wheel and tire

-chet