I don't have any first hand experience with the Bose, beyond swapping one Bose HU for another Bose HU, but I'm willing to try and help.
Are you trying to replace the "entire" system? Or are you trying to replace the HU and use the existing speakers without the old amp (at the speaker)?
If the first, I think you just have alot of work/wiring to do. If the second, I'm not sure you can (or should). From what I've read, the existing speakers are probably 1.5 ohm or something in that neighborhood, and that will quickly burn most any amp. Unless you're using a High Current amp, which I would doubt if you're planning on using the existing speakers.
Hope that helps, if not let me know and I'll try again

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