It's a really common upgrade we've done to simply add an amp and sub to an OEM system. It's especially easy if you use an amp that has high level inputs as you just get your signal directly from the rear speaker wires at the speakers. Run your power wire and a turn on lead (either an acc power or wire to a power antenna lead) and ground the amp as close to the amp as possible, wire up your sub and enjoy.
As for the fiberglass, you can likely find many tutorials online if you google it. On this forum there is one that should shed some light on the subject. I have some input on the thread but someone else started it. He build a custom molded enclosure/mount for an amplifier but pretty much the same methods would apply. My addition is for an enclosure for a single 8" sub and there are some photos of parts of the process.
Here's a link to the fiberglass tutorial on this site.
zerothread/240404