Welcome aboard, KF. It really depends on where the leak originates from. The best way to trace it is using a dye kit. Simple and effective, and available at any auto parts store.
I suspect that is a heater control valve of some sort, and probably not difficult to replace, but I'd make sure it's not leaking from elsewhere and traveling along something to get there.
Here's where you can pull the FSM for your Quest (for free), so that you can ID the exact name of the part that needs replacing:
www.nissanservicemanual.com