If you wanted to upgrade to a 2010-2017 Nav system with bluetooth and everything you could do that. You'd however need to adapt wiring (pinout, cut, splice, etc.) or
purchase a harness adapter kit, such as this one: https://www.ebay.com/itm/334124253577
Once you have the wiring in order you could then drop the parts right in.
If your main goal is to get bluetooth, there are a few alternatives in addition to what's mentioned above.
Let us know if you have any other questions.