Hey there, sorry about the delay
I would wager that the caliper was stuck first and causing a rolling thumbing noise at highway speed, if the bearing was bad it could have been most likely caused by a slowly failing caliper increasing the drag on the wheel.
The noise is usually caused by a damaged rotor, however wheel bearings are not unheard of.
Replace the caliper, pads, and rotor. They have all (most likely) been exposed to excesseive amounts of long term heat... Enough to damage the wheel bearing... Your wifes car deserves safe brakes.
Look at getting one loaded caliper and at least 1 rotor at least.