Actually on fuel injected vehicles its not as big a deal as it used to be, to run them very low (in contrast to carburated ones).
When I first buy a car I run the gas tank nearly dry and keep minute track of where the needle sits at what mileage.(carry some extra gas just in case)That way in the future I will always have a real good sense how much gas I have in the car and not think I am at a 1/4 when I am really at 40%.However most gas tanks have some dirt on the bottom, so I will change the fuel filter soon after running it <real> low.
I will go out on al imb and give u my best sense of the correct answer, online mechanics feel free to correct me, if I am wrong:
The fuel pump itself has nothing to do with your reading, its primarily the fuel level sending unit (nomenclature?), and/or wires going to and from (resistances).
Fred...
PS: I do not habitually run it real low ,to save oin stress on teh fuel pump, as well as for work related reasons, I like to keep at least a real half tank, which in most older Nissan/Infiniti is an indicated third tank