I think the weak link is going to be 2 things:
I would think the one that puts out 450HP or so would probably work on stock everything else (or at least fairly close). Of course, things blow up in a hurry when the tune isn't correct, more so than engine components blowing up. Normally it's other components that need upgraded (fuel pump, injectors, etc) that you run into issues, and then of course with higher boost you run into detonation issues due to higher compression.
The AT would at minimum need a shift kit, but if you're gonna do it you should probably just have a place like Level 10 go through the trans completely.