http://www.msefi.com is the link to all megasquirt info, guides etc.. You can find out all you need to know there.
A basic "basemap" creator is in the tuning software. Just type in your displacement, injector size, etc.. and maps will be created to get you started. Other constant settings need to be set but its all in the guides.
My ITB setup has shown great gains so far in the low end, I have not yet gotten to do much high end run/tune. As far as ease of install and setup, quite easy. Fabricating all the parts/wiring/planning etc, took a few months of my spare time but came together in one day to run the car.
The new crower selection is nice indeed.