Replaced wires? The car doesn't use plug wires but it does use coil
packs. I would pull the #1 cylinder coil pack and check the resistance
of the coil. Also (with safety glasses) start the engine with the coil
pack OFF the car and a GOOD spark plug in the coil pack. Use a coat
hanger wire (grounded off of the car body!) and create a spark between the plug and the coat hanger wire and see if it is a strong spark. This is evidence the
coil and plug are good.
For a misfire you can't limit your thinking to just one system. When you
looked at emissions, did you remove the EGR tube from the back of the
plenum? That area has been a bad place for carbon to restrict air flow
and create EGR related issues.
Are you smelling a lot of gasoline while the engine is running? This might
be a sign of injector leaking.
I have gotten the knock sensor code reading while having a misfire code. That doesn't mean the knock sensor is bad but it is probably picking up the fact the engine is misfiring and moving around.

you will get through this