egine blows a fuse after about 5 minutes of running

[inkant]

I have a 2010 Infiniti ex35 that will run for about five minutes before blowing the 15-amp fuse on port 50 in the engine bay that for the engine controls module relay

[VStar650CL]

The most likely cause is a dying spark coil whose FET is overheating and losing resistance after the engine runs awhile. Check your coils for "warts" in the epoxy. That fuse also powers the ECM, IVT solenoids, EVT mag retarders, and Evap Vent Control valve. If you don't find any warty coils, any of those could be responsible.