The KA24E and KA24DE are tough engines. Take a look around these forums. You'll see quite a few people with very high mileage engines still going strong.
As trpower7 said, you'll definitely be able to hear a problem with the chain. Keep in mind that these *are* interference engines, so you really DON'T want the chain to break. If you hear a strange noise from your engine, don't just ignore it.
The only other downsides I can think of are:
a) slightly underpowered for this application
b) somewhat loud engine
There is some good performance stuff you can do with these engines, and the noise won't matter with a nice exhaust system and an intake with a cone filter.
