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If you're seeking help, you need to provide a lot more information than the problem statement in your title. For example:

What year Q45 is this for?
How many miles on the odometer/drivetrain?
What is the maintenance history of the tranny?
What exactly is the transmission doing/not doing - is it stuck in Park?

I’ll pick up here, where the original poster left it...

2002 Q45.

I was on the freeway last night, using manual mode. 70-80 MPH. The transmission abruptly stop pulling. It’s like it was no longer in gear. Coasted off the freeway and then pushed the car to a parking space.

Now it still starts. But it won’t move in any gear, R, D, or M. It’s like there’s no transmission fluid. When I check the trannydipstick, it seems it’s overfilled. My guess is that the line may have been crimped and now the fluid isn’t circulating? It’s a novice guess, for sure. The car is lowered, which makes getting under there to check, an issue. I’m going to do that now though.

Any ideas?

All the best,
Hollywood