It's a very easy swap, but you do have to retain your 3.0 ecu, which means you have to keep your timing equipment, which means you will not have variable valve timing on the intake cams like we do. Also, it's a PITA to swap in the 6-speed because it is cable driven whereas your 5-speed transmission is rod driven and the flywheels are different. You will have to get a new clutch, though (I suggest upgrading)
People are seeing high 13s with the stock 3.5 engine swapped 4th gen 5-speed, so it's a very easy, worthwhile swap. You can get a 3.5 engine for under $1000 easily.
Very good thread with all the info you would ever need on the swap:
http://forums.maxima.org/showthread.php?t=430880
Modified by LA02MAX at 12:26 PM 11/27/2006
Modified by LA02MAX at 12:27 PM 11/27/2006